OptimalAmino®
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Fasted Training — Does It Help or Hurt?

Fasted training has a genuine metabolic upside — and a genuine anabolic downside. EAAs may let you have both.

Training in a fasted state increases fat oxidation during exercise. This is well-established and not controversial. Aird et al. (2018) conducted a systematic review in the Journal of the International Society of Sports Nutrition and confirmed that exercising in the fasted state increases fat utilization compared to fed exercise.

The downside: fasted exercise also suppresses muscle protein synthesis. Without circulating amino acids, exercise-induced MPS is blunted, and net protein balance remains negative for longer. Cortisol is elevated, and the catabolic-to-anabolic transition is delayed.

The EAA workaround

A small dose of EAAs (10–12g) consumed 15–30 minutes before fasted training provides circulating amino acids to support MPS without the insulin spike from a full meal. The caloric impact is minimal (~40–50 calories), which may preserve some of the enhanced fat oxidation benefits while preventing the catabolic penalty.

This approach is theoretical but mechanistically sound: you’re providing the substrate needed for protein synthesis (EAAs) without the macronutrient load (carbohydrates and fats) that would shift fuel utilization away from fat stores. It’s the best available compromise for athletes who want the fat-burning advantage of fasted training without sacrificing muscle.

References

  1. Aird TP, Davies RW, Carson BP. Effects of fasted vs fed-state exercise on performance and post-exercise metabolism: a systematic review and meta-analysis. Scand J Med Sci Sports. 2018;28(5):1476-1493. PubMed
  2. Schoenfeld BJ. Does cardio after an overnight fast maximize fat loss? Strength Cond J. 2011;33(1):23-25.

A small EAA dose before fasted training provides the substrate without the caloric load. OptimalAmino fits the window.

Available in tablets and powder. HSA/FSA eligible.

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